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Buy medicine Panadol Extra by online form and therapeutic indications

Panadol Extra pills refer to combined preparations containing paracetamol and caffeine. The medication has analgesic and antipyretic effect. Paracetamol medicine group NSAIDs reduces prostaglandin levels in the CNS by inhibiting the enzyme cyclooxygenase. Caffeine enhances the pharmacological effects of paracetamol. Cheap Panadol Extra indications for use are headache, including migraine headache, toothache, neuralgia, rheumatic pain, recurrent pain in women; to relieve cold and flu symptoms, sore throat.

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  • Panadol Extra 500mg


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Cheap Panadol Extra pills are usually well tolerated by patients, in some cases, it is mentioned development of such side effects:

  • immune system: anaphylaxis, hypersensitivity reactions, including rash on the skin and mucous membranes, angioedema, pruritus, angioedema, erythema multiforme exudative, toxic epidermal necrolysis;
  • on the part of the digestive system: nausea, vomiting, heartburn, epigastric pain;
  • endocrine system: hypoglycemia, up to hypoglycemic coma;
  • blood system and lymphatic system: thrombocytopenia, agranulocytosis, anemia, hemolytic anemia, bruising or bleeding;
  • cardiovascular system: tachycardia, arrhythmia, increased blood pressure, heart palpitations;
  • central nervous system: insomnia, anxiety, dizziness;
  • respiratory system: bronchospasm in patients sensitive to aspirin.

Interaction with various medicinal products includes:

  • the rate of absorption of active substance may be increased by the use of metoclopramide and domperidone, and decrease with the using of cholestyramine;
  • barbiturates reduce the antipyretic effect of paracetamol;
  • the simultaneous use of high doses of paracetamol with isoniazid increases the
  • risk of hepatotoxic syndrome;
  • Panadol Extra Advance reduces the effectiveness of diuretics;
  • do not use with alcohol.

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The duration of treatment and the doses are determined by the attending physician for each patient individually. Adults and adolescents aged over 12 years are usually prescribed to 500-1000 mg (2 tablets or 2 caplets or tablets effervescent 2) 3-4 times a day at intervals of not less than 4 hours. The maximum daily Panadol tablet amount is 4000 mg (8 tablets). The drug for more than 3 consecutive days is possible only for the purpose of the attending doctor. During treatment with this medication people should not eat large amounts of beverages containing caffeine. Symptoms of Panadol Extra tablet overdosage in the first 24 hours are pallor, anorexia, vomiting, and abdominal pain or nausea. In severe poisoning hepatic failure can progress to encephalopathy, hemorrhage, hypoglycemia, coma and be fatal. There were also heart arrhythmia and pancreatitis. In case of overdosing patient requires emergency medical care. The patients should be immediately taken to hospital, even if there are no early these symptoms.

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