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Muscle tissue has the properties of contraction and relaxation. Sometimes muscle can long remain in a reduced state - there is the so-called muscle spasm. It gives a person the discomfort and sometimes pain. To eliminate such states humans use a special group of muscle relaxant drugs. All muscular relaxants are divided into two groups depending on the application of their action points. The first group includes centrally action agents - they affect the first motor neurons located in the brain and spinal cord. The second group contains peripherally acting muscle relaxants drugs - they violate the chemical reactions in the neuromuscular synapses (junctions of nerve endings and muscles). Centrally acting medications differ in their chemical structure and peripherally acting medicines - by the ability to alter the electrical activity at the synapse. Indications for use of muscle relaxer medication with a lot of action are neurological diseases accompanied by persistent muscle spasm; surgical intervention requiring complete muscle relaxation; diagnostic activities that require immobility of the patient; electroconvulsive therapy; prevention of muscle rupture in fractures; reposition of bone fragments; for intubation; when the difficulties of endoscopic examinations.
Carisoprodol medicine is a powerful muscle relaxant; it is often used for recovery from severe muscle damage. It is used for relaxation of striated muscle, regulates their tone, affecting the nervous system. The effect of this drug is due to the fact that the components of the medicament to block neural impulses sent to the brain.
Flexeril medication is wide-spread as one of central acting muscular relaxants group that remove redundant muscle tension, decrease the severity of pain, and in this way patients feel motor function improvement. People use the medicament for relief of muscle spasms, arthrosis, movement disorder.
Soma is one of neuromuscular relaxants’ groups. Generally receiving this preparation people feel a relief of pain and muscle spasms, as well as the flexibility of the spine increases. Muscle aches can occur for a variety of reasons: injuries from sports, traffic accidents, everyday stress.
Zanaflex generic name is accepted with increased muscle tone, which is caused by neurological disorders (degenerative changes in the spinal cord, multiple sclerosis, cerebral palsy, blood circulation disorder in the brain); with functional diseases of the spine (after surgical treatment of the spine); in restoring the body after surgery (for example, after removal of herniated discs).
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Muscle relaxer drugs are widely used in neurological practice, with applying only centrally action means. They are appointed for the treatment of the following diseases: osteochondrosis with severe muscle spasm; pain in herniated disk; muscle contracture; spinal cord disease with the development of muscle spasms - syringomyelia, trauma and spinal cord tumors; strokes with spastic paresis. The choice of the central muscle relaxant medication is due to the fact that the point of application of their actions is the spinal cord. Patients must take into account that in the presence of the following factors as hypercapnia, hypoxia, hypokalemia, hypotension, hypothermia, impaired microcirculation, metabolic acidosis, deep anesthesia, advanced age and some others, action time of muscle relaxants may increase.
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Requirements for modern preparations are to ensure prompt action and blockade of neuromuscular transmission. It should not affect the cardiovascular system. Especially stringent requirement is to apply drugs for muscle spasm in anesthesia. Their impact is in full relaxation of muscles and the termination of the patient's own breathing, for mechanical ventilation. Muscle relaxants of central action well affect almost all departments of the central nervous system. A list of the best muscle relaxer is well-known as Soma, Carisoprodol, Flexeril, Lioresal, Robaxin and many others. Therefore, before using them you should consult with your doctor because these medical products can commonly cause adverse reactions. However despite the fact that the intake of such drugs will not significantly harm humans, the threat of certain side effects still exists.
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